Orbital pseudotumor
Idiopathic orbital inflammatory syndrome (IOIS); Non-specific orbital inflammationOrbital pseudotumor is the swelling of tissue behind the eye in an area called the orbit. The orbit is the hollow space in the skull where the eye sits. The orbit protects the eyeball and the muscles and tissue that surround it. Orbital pseudotumor does not spread to other tissues or places in the body.
Causes
The cause is unknown. It mostly affects young women, although it can occur at any age.
Symptoms
Symptoms may include:
- Pain in eye, and it may be severe
- Restricted eye movement
- Decreased vision
- Double vision
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Eye swelling (proptosis)
Eye swelling
Bulging eyes is the abnormal protrusion (bulging out) of one or both eyeballs.
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Exams and Tests
The health care provider will examine your eye. If you have signs of pseudotumor, additional tests will be done to make sure you don't have other conditions that may look like pseudotumor. The two most common other conditions are:
- A cancerous tumor in the orbit
- Thyroid eye disease
Tests may include:
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CT scan of the head
CT scan of the head
A head computed tomography (CT) scan uses many x-rays to create pictures of the head, including the skull, brain, eye sockets, and sinuses.
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MRI of the head
MRI of the head
A head MRI (magnetic resonance imaging) is an imaging test that uses powerful magnets and radio waves to create pictures of the brain and surrounding...
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Ultrasound of the head
Ultrasound
Ultrasound uses high-frequency sound waves to make images of organs and structures inside the body.
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Skull x-ray
Skull x-ray
A skull x-ray is a picture of the bones surrounding the brain, including the facial bones, the nose, and the sinuses.
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Biopsy
Biopsy
A biopsy is the removal of a small piece of tissue for lab examination.
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Treatment
Mild cases may go away without treatment. More severe cases most often respond well to corticosteroid treatment. If the condition is very bad, the swelling may put pressure on the eyeball and damage it. Surgery may be needed to remove part of the bones of the orbit to relieve the pressure.
Outlook (Prognosis)
Most cases are mild and outcomes are good. Severe cases may not respond well to treatment and there may be some loss of vision. Orbital pseudotumor most often involves only one eye.
Possible Complications
Severe cases of orbital pseudotumor may push the eye forward so much that the lids cannot cover and protect the cornea. This causes the eye to dry out. The cornea may become cloudy or develop an ulcer. Also, the eye muscles may not be able to properly aim the eye which can cause double vision.
When to Contact a Medical Professional
People with this condition need regular follow-up care with an eye doctor who is familiar with the treatment of orbital disease.
Contact your provider right away if you have any of the following problems:
- Irritation of the cornea
- Redness
- Pain
- Decreased vision
References
Cioffi GA, Liebmann JM. Diseases of the visual system. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 391.
McNab AA. Orbital infection and inflammation. In: Yanoff M, Duker JS, eds. Ophthalmology. 6th ed. Philadelphia, PA: Elsevier; 2023:chap 12.14.
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Skull anatomy - illustration
The skull is anterior to the spinal column and is the bony structure that encases the brain. Its purpose is to protect the brain and allow attachments for the facial muscles. The two regions of the skull are the cranial and facial region. The cranial portion is the part of the skull that directly houses the brain and the facial portion includes the rest of the bones of the skull.
Skull anatomy
illustration
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Skull anatomy - illustration
The skull is anterior to the spinal column and is the bony structure that encases the brain. Its purpose is to protect the brain and allow attachments for the facial muscles. The two regions of the skull are the cranial and facial region. The cranial portion is the part of the skull that directly houses the brain and the facial portion includes the rest of the bones of the skull.
Skull anatomy
illustration
Review Date: 8/5/2024
Reviewed By: Franklin W. Lusby, MD, Ophthalmologist, Lusby Vision Institute, La Jolla, CA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
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